KANSAS CITY— Omar Infante’s slow infield squibber plated Alex Rios with the go-ahead run in the eighth inning and right-hander Ryan Madson closed out the ninth as the Royals held off the White Sox, 5-4, on Sunday to sweep the three-game series.

With runners on second and third and one out, Infante hit a jam shot toward first baseman Jose Abreu, whose throw home was late to get Rios.

Madson filled in for Greg Holland, who had pitched the previous two nights, to record his second save of the season. Madson had 32 saves in 2011.

Danny Duffy started for the Royals but shaky command led manager Ned Yost to pull him after 3 1/3 innings with the score tied, 3-3. Kris Medlen entered and was phenomenal, allowing no hits and no runs through 3 2/3 innings. Medlen struck out three.

“It was just a day you say you didn’t have it,” Duffy said. “Ned managed a really good game and brought in Med and we won.

“I know what I can do. Today is just one of those days. I really have found my slot, but today I just wasn’t able to execute. I couldn’t put the ball where I wanted to.”

White Sox starter Jose Quintana went 6 2/3 innings, giving up eight hits and four runs. He walked two and struck out four.

“With ‘Q’, it was tough getting out of that first inning,” White Sox manager Robin Ventura said. “They knocked him around a little bit. We battled back and wound up tying it a couple of times. Their guys just ended up chipping away right there at the end.”