American League
Indians 1, Red Sox 0
CLEVELAND (AP) — The winless Boston Red Sox lost their sixth in a row when the Cleveland Indians squeezed home the only run in the eighth inning, then trapped pinch-runner Darnell McDonald off second base for the final out Thursday in a 1-0 victory.
The Red Sox are off their worst start since 1945, when they lost a team-record eight straight. Boston, favored by many to win the World Series, returns to Fenway Park for its home opener Friday against the New York Yankees.
Asdrubal Cabrera’s suicide-squeeze bunt off Daniel Bard (0-2) put the Indians ahead in their fourth straight victory.
David Ortiz drew a two-out walk in the Boston ninth and McDonald ran for him. J.D. Drew bounced a single that ricocheted off pitcher Chris Perez and went to third baseman Adam Everett.
McDonald rounded second base too far, fell down and tried to scramble back to the bag. Everett, who had come in to field the carom, made a snap throw to second baseman Orlando Cabrera that nailed McDonald.
Rafael Perez (2-0) retired two batters in the eighth. Chris Perez pitched the ninth for his second save.
Starting pitchers Fausto Carmona of the Indians and Jon Lester each pitched seven shutout innings.

Orioles 9, Tigers 5
BALTIMORE — Adam Jones homered and drove in three runs, Mark Reynolds also had three RBIs, and Baltimore used a five-run seventh inning to beat Detroit.
Vladimir Guerrero hit his first home run with the Orioles, who took two of three from the Tigers after opening the season with a three-game sweep in Tampa Bay.
Alex Avila homered for the Tigers, who host Kansas City on Friday after going 2-4 on the road to open the season.
Baltimore sent 10 batters to the plate in the seventh. After Brian Roberts and Nick Markakis reached against Brad Thomas (0-1), Guerrero singled in a run off Enrique Gonzalez and Jones hit a sacrifice fly for a 6-5 lead. Reynolds followed with a two-run double and Cesar Izturis capped the uprising with an RBI single.
Jim Johnson (1-0) pitched 1 2-3 innings of one-hit relief for Baltimore.

White Sox 5, Rays 1
CHICAGO — Edwin Jackson struck out a career-high 13 and the Chicago White Sox took their home opener by sending the winless Tampa Bay Rays to their sixth straight loss.
The AL East champion Rays extended the worst start in team history — they haven’t even held a lead yet this year. Tampa Bay has scored exactly one run in five of its defeats.
Jackson (2-0), who pitched a no-hitter against Tampa Bay last season while with Arizona, allowed four hits in eight innings. David Price (0-2) took the loss.
At 0-6, the Rays have totaled only eight runs and 27 hits. They are tied for the worst record in the majors with Boston, the only other winless team in the major.
Rays slugger Manny Ramirez missed the game because of a family matter but should be ready for Friday night’s game.

Yankees 4, Twins 3
NEW YORK — Derek Jeter passed Rogers Hornsby for 33rd place on baseball’s all-time list with two hits, and the New York Yankees’ relievers held off the Minnesota Twins in their first game since blowing a big lead.
The Twins lost heralded Japanese import Tsuyoshi Nishioka to a broken left leg when Nick Swisher slid into him at second base while breaking up a double play. Swisher slid well to the left of the bag as Nishioka tried to make the turn.
The Twins said the play was clean, and Swisher apologized to Nishioka for the hard slide. Nishioka was put on the 15-day disabled list and there’s no timetable for his return.
A.J. Burnett (2-0) improved to 7-0 in 12 April starts for the Yankees, allowing two runs on five hits in six innings.
With the Yankees up 4-3, Rafael Soriano pitched a scoreless eighth two days after he surrendered a 4-0 lead in a game Minnesota won in extra innings. Mariano Rivera closed for his fourth save.
Francisco Liriano (0-2) allowed four runs on four hits and three walks in five innings.

Athletcs 2, Blue Jays 1
TORONTO — Trevor Cahill pitched eight strong innings for his first win of the season, Conor Jackson singled home the go-ahead run and the Oakland Athletics beat the Toronto Blue Jays.
Cahill (1-0) came in 0-2 with an 8.04 ERA in three starts against Toronto, but kept the Blue Jays in check. He allowed one run and three hits, walked none with seven strikeouts.
Brian Fuentes closed it out for his first save as the Athletics avoided a three-game sweep.
Oakland trailed 1-0 going into the eighth when Andy LaRoche led off with a double and advanced to third on Cliff Pennington’s sacrifice. Jason Frasor (1-1) replaced starter Ricky Romero and fanned Coco Crisp, but strike three was a wild pitch that bounced away from J.P. Arencibia, allowing LaRoche to score and Crisp to move safely to first.
Crisp stole second and third before scoring on Jackson’s single.

National League
Astros 3, Reds 2
CINCINNATI — Matt Downs doubled home the tiebreaking run with two outs in the ninth inning on Thursday and the Houston Astros held on for their first win of the season, 3-2 over the previously unbeaten Cincinnati Reds.
The Astros were the last NL team to win a game, and they did it with a little drama.
Downs, who had struck out in all three of his at-bats this season, doubled off Nick Masset (0-1) for the lead. Closer Brandon Lyon, who blew his only other save chance on opening day, gave up a pair of two-out singles before getting pinch-hitter Ramon Hernandez to ground into a forceout.
The Reds won their first five games for the first time since 1990. They were the lone NL team left without a loss — Texas is still perfect in the AL.
Left-hander Fernando Abad (1-0) got his first major league win in relief of Brett Myers, who pitched into the seventh inning, when he gave up Scott Rolen’s tying pinch-hit homer.
It was a particularly sweet win for Houston, which dropped its first eight last season — one shy of the club record — and lost five in a row to start this season.

Phillies 11, Mets 0
PHILADELPHIA — Roy Halladay pitched seven sharp innings for his first win of the season, Wilson Valdez had a career-high four hits, and the Philadelphia Phillies beat the New York Mets.
Halladay (1-0) allowed six hits and struck out seven. The reigning NL Cy Young Award winner gave up one run in six innings in the opener against Houston, and avoided a loss when the Phillies rallied in the ninth for a 5-4 win.
The four-time NL East champions are off to a 5-1 start.
Jonathon Niese (0-1) got roughed up by an offense that’s averaging 7.2 runs and 12.7 hits per game. The left-hander allowed six runs and eight hits in four innings.
The Mets head to Citi Field for their home opener Friday against Washington after splitting a six-game road trip.

Brewers 4, Braves 2
MILWAUKEE — Nyjer Morgan jarred the ball loose in a collision at home to give Milwaukee the lead in the second inning, and the Brewers went on to beat the Atlanta Braves for their third straight win.
Ryan Braun hit his third home run of the season for the Brewers, who have recovered nicely from a four-game losing streak to start the year. Milwaukee rallied to take three of four games from the Braves after losing Monday’s home opener at Miller Park.
Martin Prado had a two-run single for Atlanta, which will hold its home opener Friday night after playing its first seven games on the road.
Milwaukee got a better outing the second time around from new starter Shaun Marcum (1-1), who gave up two runs, five hits and two walks with four strikeouts in six innings.
Brewers closer John Axford pitched a scoreless ninth to earn saves in back-to-back games after a shaky start to the season.
Atlanta couldn’t muster much run support for starter Tommy Hanson (0-2).

Rockies 7, Pirates 1
PITTSBURGH — Esmil Rogers allowed four singles while pitching into the eighth inning, Troy Tulowitzki homered and drove in three runs, and the Colorado Rockies beat Pittsburgh to wreck the Pirates’ home opener under new manager Clint Hurdle.
Rogers (1-0) won the Rockies’ No. 5 job with a strong finish in spring training. He looked more like their ace, mixing a devastating 95 mph fastball with a few breaking pitches to overwhelm the Pirates over 7 1-3 dominant innings. After giving up singles to the first two batters, the right-hander retired 22 of 23, including 18 straight.
Tulowitzki connected for his third homer in the fourth off Paul Maholm (0-1) to make it 3-1 as the Rockies won their fourth straight.

Nationals 5, Marlins 3, 11 innings
MIAMI — Adam LaRoche snapped a slump with a two-run homer in the 11th inning Thursday, and Washington salvaged the final game of the series.
LaRoche was 3 for 23 before he hit his first homer of the year off Edward Mujica (1-1). That ended a streak of 12 2-3 scoreless innings for Florida’s bullpen in the series.
The Marlins gave up two unearned runs, struck out 12 times and went 1 for 11 with runners in scoring position.
Jayson Werth hit his first home run since signing a $126 million, seven-year contract to join the Nationals.
Todd Coffey (1-0) pitched a perfect 10th. Sean Burnett pitched the 11th for his second save.